Marie O’Toole  began her career serving as a staff nurse, and subsequently assistant head nurse and a staff development instructor at the Hospital at the University of Pennsylvania in the 1970s. She first joined the Rutgers–Camden faculty as an instructor in 1978, embarking on a successful academic career spanning several notable institutions. She returned to Rutgers–Camden from 1998 to 2004 as an associate professor of nursing and program coordinator for the graduate program and again in 2010. 

She is passionate about advancing nursing education in an international, interdisciplinary, and collaborative fashion. In the mid-1990s, she was the founding chair of Nurses Overseas, a division of Health Volunteers Overseas that provides an opportunity for nurse faculty to work with their colleagues in developing countries. In 2007, she served as the principal investigator for a grant funded by the U.S. Department of Education and the European Commission’s Directorate General for Education and Culture to develop programs with Semmelweis University in Hungary and Laurea University of Applied Sciences in Finland.

More recently, O’Toole was the recipient of a 2016-2017 Fulbright Specialist grant in education that allowed her to teach and study at Jordan University of Science and Technology in Irbid, Jordan.

She has garnered numerous awards, including an honorary doctorate from Semmelweis University in Budapest and the Call to Service Award from former President George W. Bush. In 2018, she was one of 16 nurses selected nationwide for induction into the National League of Nursing’s prestigious Academy of Nursing Education.

O’Toole holds bachelor’s and master’s degrees from the University of Pennsylvania School of Nursing and a doctorate from the Rutgers Graduate School of Education in New Brunswick.

Her primary program of research is academic lexicography. O'Toole has served as the editor of multiple editions of dictionaries and encyclopedias, including the award winning Mosby Dictionary of Medicine, Nursing and Health Professions.  She continues to edit the Mosby series of dictionaries.